Prostate-specific membrane antigen-based imaging

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Prostate-specific membrane antigen-based imaging.

Prostate cancer (CaP) is the most common noncutaneous malignancy affecting men in North America. Despite significant efforts, conventional imaging of CaP does not contribute to patient management as much as imaging performed for other common cancers. Given the lack of specificity in conventional imaging techniques, one possible solution is to screen for CaP-specific antigenic targets and genera...

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Prostate-Specific Membrane Antigen-Based Therapeutics

Prostate cancer (PC) is the most common noncutaneous malignancy affecting men in the US, leading to significant morbidity and mortality. While significant therapeutic advances have been made, available systemic therapeutic options are lacking. Prostate-specific membrane antigen (PSMA) is a highly-restricted prostate cell-surface antigen that may be targeted. While initial anti-PSMA monoclonal a...

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ژورنال

عنوان ژورنال: Urologic Oncology: Seminars and Original Investigations

سال: 2013

ISSN: 1078-1439

DOI: 10.1016/j.urolonc.2012.04.016